Simple Pathway
The Amish may lead a simple life, but they're helping scientists understand one of the most complicated molecular pathways in autism.Genetic studies have fingered hundreds of variations linked to autism, so it's understandably exciting when several turn out to belong to the same network. One of the most studied (and most therapeutically promising) pathways is mTOR, short for molecular target of rapamycin.A new study of an extremely rare form of epilepsy found in Amish groups adds heft to the idea that mTOR is an important biochemical player in autism.Read more at...SFARI, June 2010.