There are several short periods during development in which our brains are 'plastic' — meaning that neuronal connections appear and disappear depending on how much they are used.The brain can only adapt to new experiences during these windows of plasticity. But researchers may have found a way to reopen the windows, according to a paper published late last month in Science.The visual system is the best platform to study plasticity. For example, if you shut one eye of a mouse during a 'critical period' of development, around the 28th day of its life, its brain will rewire so that it only processes light from the other eye. In the 1970s, scientists Tortsen Wiesel and David Hubel were the first to demonstrate this phenomenon in a one-week-old kitten. This critical period also exists in people.A decade ago, scientists discovered that plasticity can be induced or delayed by drugs that mimic inhibitory interneurons — cells that dampen nerve impulses.In the new study, the researchers transplanted fetal interneurons into the brains of young mice and shut one of the animals' eyes during the normal critical period. After the window closed, the researchers opened the eye and, as expected, the mouse could not see from it.Read more at...SFARI, March 2010.