Creatures Great and Small
Among animal models of autism, the mouse reigns supreme: scientists have manipulated dozens of autism risk genes in the furry critters.But the biggest findings in autism may well come from tinier brains.In a review published 30 March in Molecular Psychiatry, a group of Australian researchers argues that flies, bees, worms and fish have much to offer psychiatric research.Even the most primitive nervous systems share some important features with ours. Synapses in the worm Caenorhabditis elegans, for instance, relay chemical messages using the same neurotransmitters we do. The layout of various brain regions in humans and zebrafish is also remarkably similar.Read more at...SFARI, May 2010.