Courtesy: U. of Washington Institute for Learning & Brain Sciences
In typical conversation, people speak at a rate of 250 milliseconds per syllable. So imagine how confusing it would be if you lagged behind — even if only by a fraction of a second.
That tiny delay may be what’s provoking the language problems in some children with autism.
Tim Roberts, a radiologist at the Children’s Hospital of Philadelphia, has been studying the phenomenon for the last decade. He uses magnetoencephalography, or MEG, the ‘hair dryer’ brain imaging method that uses magnetic fields to detect changes in brain activity on the order of 10 milliseconds or less.
Last week, his team reported that when listening to tones of different frequencies, children with autism give brain responses in their right hemispheres about 11 milliseconds slower than healthy controls do. In other, unpublished work, Roberts found a much longer delay — about 50 milliseconds — when children with the disorder process speech sounds, such as ‘ah’ or ‘ou’.
The average age of children in the study was 10 years. If the findings are similar in babies and toddlers with autism, Roberts says this lag measurement may be a reliable marker for diagnosing the disorder, even before other symptoms appear.
MEG would be particularly useful for young children because it’s non-invasive and doesn’t require them to perform a difficult task. On the downside, a MEG scan isn’t a realistic option for the majority of children with autism — there are only about 100 machines worldwide.

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January 15, 2010 at 12:18 am
MJ
Just out of curiosity, do you know whether an acoustic brainstem response (ABR) test would show a delay in auditory processing or what the difference between the that test and the MEG would be? I know that they both measure brain activity from sound but I have not been able to find a good description of how their measurements would differ.
January 15, 2010 at 3:05 pm
virginiahughes
Hi MJ,
I’m not sure that they would necessarily show the same thing. ABR measures electrical changes from the brain stem, whereas MEG measures magnetic field changes (in this case, from the right hemisphere).
Here’s a webpage with some background on ABR, which may be interesting for you:
http://emedicine.medscape.com/article/836277-overview