I found a delicious historical nugget tonight while researching for an article-in-progress about the link between autism and prenatal infection.
In 1971, Stella Chess published a paper about the 1964 rubella epidemic in New York City. She found that an unusually high number of kids with autism in 1970 were born to women who had been infected with rubella. That’s interesting (especially for my article). But what really shocked me was something Chess mentioned briefly at the end of the introduction:
A 1964 British survey of children in Middlesex aged 8 to 10 years found that 4.5 per 10,000 children were autistic….We recognize that the diagnosis of autism requires rigorous justification. The condition is often loosely defined and overdiagnosed.
Wait a minute…4.5 per 10,000 and she thought doctors were overdiagnosing? Now a half-century since that survey, autism is found in about 1 of every 150 kids, and most researchers I’ve interviewed say that even that is probably an underestimate.
Of course, now I’m going to get a few anti-vaxers in the comments telling me that this is evidence of an “autism epidemic” in the last few decades. This is almost certainly not true, as I’ve reported twice. Still, it’s interesting to see how the field’s perspective has changed since then. And how it hasn’t: Autism, unfortunately, is still “often loosely defined.”

“At least since Dante’s Paolo and Francesca fell in love over tales of Lancelot,” 
