Archives for the month of: December, 2007

In May 2002, on an isolated hilltop in Delphi overlooking the Aegean Sea, several dozen scientists convened to discuss how the cerebral cortex, the brain’s outer layer, develops.

It was there, at the site of the legendary Greek oracle, that Gordon Fishell reached a turning point in his career.

Fishell, then 42, had been studying how the developmental environment in a mouse embryo influences how stem cells turn into different types of interneurons ― the intriguing cells that dampen electrical signaling in the brain1. But he needed help understanding the next step: measuring the activity of fully developed interneurons.

He found his answer in conference organizer Arnold Kriegstein, then a Columbia University physiologist renowned for his brain-cell recording techniques. Soon after the Delphi meeting, on a much noisier island five thousand miles west, the two scientists began what Fishell now calls the “taxi cab collaboration.”

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SFARI, December 2007.

Three years after airing a documentary that claimed HIV-positive orphans were exploited in clinical trials of AIDS drugs, the BBC has apologized. The apology is a response to complaints by several prominent AIDS scientists that the video, Guinea Pig Kids, primarily aired the views of AIDS denialists, who don’t believe that the HIV virus causes AIDS.

“The BBC has produced thousands of hours of current affairs programming since 2004. This was a blip, which is why it’s been taken so seriously,” says BBC spokesman Mark Ogle. The BBC has formed a committee to investigate “why these editorial lapses occurred,” Ogle says, and the committee’s findings will eventually be “prominently displayed” on the documentary’s BBC website.

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Nature Medicine, December 2007.

Last December, two days before opening night of the BSO’s Holiday Spectacular, a package was delivered to executive producer Dori Armor and costume designer David Burdick: 10 pairs of gold leather elf shoes.“They were all handmade for each elf. It took a month to make them,”Armor recalls. The team soon discovered, however, that the shoes for the largest elf—“he was the size of a football player,” Armor says—were much too small.

It was down-to-the-wire decision time for Armor: Should the largest elf just wear a different pair?

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Overture, December 2007 (Cover).

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